Literature Review

Enabled the client to
understand the device
based landscape of the
disease space and enable
them to take evidence ...

I served as a consultant with Orbees Medical one of the recent projects focused on evaluating a new therapeutic space for a large medical device company...
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Physician at a top teaching Facility in SF Bay Area

Literature Review

In the current scenario of greater demand for cost effective products and solutions by the market, and focus on evidence by regulators, physicians, and payors , Orbees helps clients in making evidence-based medicine backed business decisions that meet the market expectations

Literature review is a labor-intensive endeavor and demands a very careful and meticulous methodology to make it comprehensive and corroborated with multiple sources that are authentic. It entails an evidence based medicine approach towards a systematic review of:

Disease and clinical space
Novel therapies
New products
Clinical trials and observational studies
Guidelines and regulatory process

At Orbees Medical, we follow an extensive systematic literature review process to provide clinical evidence-backed analysis of safety and efficacy of novel interventions, clinical protocols, therapy evolution, clinical trials and regulatory/reimbursement scenario. Depending up on the project and space, we identify and review from a few dozens to several hundreds of articles. Orbees process includes the following steps:

Orbees process includes the following steps:

Identification of published & unpublished literature

Targeted literature search using clusters of key words. The sources for the literature includes medical and scientific journals, clinical trials databases, books, publications by regulatory bodies, websites of companies developing competitive products and leading research institutions, conference proceedings (abstracts, posters, podium and powerpoint presentations), personal communications (if any), market research reports, patent databases, and reports by industry analysts.

Selection of the literature identified

Each piece of literature is assessed for eligibility on the basis of relevant inclusion criteria

Quality assessment of selected literature

The quality of the selected literature is evaluated on the basis of various parameters such as:

Impact factor
Eigen factor
H Index

Synthesis of findings from the assessed literature

The assessed literature is analyzed for relevant findings

Presentation of the findings

The findings from the individual studies are then aggregated and analyzed to identify trends and patterns and provide evidence backed inferences and insights.